Pulpdent’s ACTIVA™ BioACTIVE – your questions answered


Fred Berk, Vice President of Pulpdent, answers some frequently asked questions about ACTIVA™ BioACTIVE and why it is set to revolutionise restorative dentistry.


ACTIVA™ BioACTIVE products from Pulpdent are aesthetic, dental restorative materials that behave in a manner similar to that of natural teeth. They are flowable, resin-based bioactive restoratives with the same indications as traditional and flowable composites, and syringe-dispensing provides ease of application. These innovative bioactive products stimulate the formation of hydroxyapatite and chemically bond to teeth, helping to seal them against secondary decay.

What are bioactive materials?

Bioactive dental materials imitate nature, play a dynamic role in the mouth and deliver the minerals teeth need to stay healthy. They are moisture-friendly materials that stimulate the natural remineralisation process with the release and recharge of beneficial ions, such as calcium, phosphate and fluoride. In the presence of saliva, they elicit a biological response that forms a layer of apatite and a natural bond at the material-tooth interface.

How was ACTIVA™ BioACTIVE developed?

ACTIVA™ BioACTIVE was developed over the course of almost 20 years. The mouth is a wet environment, but traditional dental resins are hydrophobic. We had a different idea and developed resin materials that are moisture tolerant and work favorably in the moist oral environment.

We looked at provisional materials and saw that acrylics and bisacrylics were brittle. We recognised that there was a need for more fracture-resistant materials. We synthesized a new molecule, which we patented, by splicing a synthetic rubber molecule into a diurethane dimethacrylate molecule. Studies consistently show that the addition of this molecule to a resin provides far greater toughness, fracture resistance, deflection at break, flexural strength, and flexural fatigue values than all other dental materials.

We are processing glass and silica fillers for composite materials all the time. Our research team began to put these various chemistries and fillers together in different ways to develop products for various dental applications. This is how ACTIVA was born.

How do ACTIVA and bioactive materials differ from passive materials?

Bioactive materials are moisture-friendly and have the ability to transport or store water, which is an essential requirement of bioactivity, because biochemistry only occurs in the presence of water. Bioactive materials can play a dynamic role in the mouth and respond to pH changes in the oral environment. They release and recharge their ionic components, providing teeth with the essential minerals they need to stay healthy. This makes them completely different from passive materials, such as traditional composites, which are hydrophobic, repel water, do not stimulate remineralisation, and have no capacity for bioactivity. Traditional materials are designed to be neutral and do no harm, and as a result, they do not provide any benefits other than filling a space for function and aesthetic purposes.

Why should a dentist switch to ACTIVA™ BioACTIVE?

How are ACTIVA and bioactive materials used clinically?

There are different categories of bioactive materials for various indications. Most are non-aesthetic materials used for endodontic purposes, as dentine replacement materials, or for cementation. These would include calcium-based materials, such as calcium hydroxide, calcium silicate (MTA) and calcium aluminate. ACTIVA™ BioACTIVE materials are the only aesthetic bioactive restorative materials. They are dispensed directly from the syringe like any flowable composite and can be used to restore all classes of cavities.

How does the dentist benefit from ACTIVA?

The greatest cost to a dentist is time. Materials represent only about 6 per cent of revenue in practice, and the cost of bioactive materials is comparable to passive materials. Meanwhile, the injection technique used with ACTIVA™ BioACTIVE takes a fraction of the time of placing a traditional composite.  In cases where there is sufficient retention form in the cavity preparation, ACTIVA™ BioACTIVE does not require a bonding agent, which saves considerable time and money. We are seeing cases that are more than four years old, and they look the same as they did the day they were placed. Dentists have observed that ACTIVA™ BioACTIVE has an affinity for tooth structure and “appears to melt into the tooth.”  This penetration and intimate adaptation to tooth structure has never been seen before with an aesthetic restorative resin material. The result is improved marginal integrity and long-term outcomes, and that means happy patients.

Where can ACTIVA™ BioACTIVE be bought in the UK?

ACTIVA™ BioACTIVE products from Pulpdent are distributed in the UK by Prestige Dental. For more information, please contact Rachel Jane on 07879 140286, email rachelj@prestige-dental.co.uk or contact@pulpdent.uk, or visit www.pulpdent.uk.